Xavier Pivot Selected Research

Lapatinib (GW572016)

5/2015	CEREBEL (EGF111438): A Phase III, Randomized, Open-Label Study of Lapatinib Plus Capecitabine Versus Trastuzumab Plus Capecitabine in Patients With Human Epidermal Growth Factor Receptor 2-Positive Metastatic Breast Cancer.
6/2013	Phase II study assessing lapatinib added to letrozole in patients with progressive disease under aromatase inhibitor in metastatic breast cancer-Study BES 06.
9/2011	Combining molecular targeted therapies: clinical experience.
11/2009	Lapatinib combined with letrozole versus letrozole and placebo as first-line therapy for postmenopausal hormone receptor-positive metastatic breast cancer.

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Xavier Pivot Research Topics

Disease

97	Breast Neoplasms (Breast Cancer) 03/2024 - 10/2006
49	Neoplasms (Cancer) 03/2024 - 04/2002
11	Neoplasm Metastasis (Metastasis) 05/2022 - 12/2011
9	Disease Progression 11/2021 - 05/2008
6	Triple Negative Breast Neoplasms 01/2023 - 09/2013
6	Cardiotoxicity 08/2022 - 03/2010
6	Colorectal Neoplasms (Colorectal Cancer) 11/2021 - 06/2006
6	Neutropenia 01/2018 - 07/2011
6	Carcinoma (Carcinomatosis) 08/2014 - 01/2003
5	Fatigue 07/2023 - 06/2017
5	Cardiovascular Diseases (Cardiovascular Disease) 01/2023 - 07/2013
5	Prostatic Neoplasms (Prostate Cancer) 08/2016 - 01/2011
5	Ovarian Neoplasms (Ovarian Cancer) 06/2011 - 10/2005
4	Pain (Aches) 12/2020 - 12/2011
4	Diarrhea 09/2017 - 11/2009
4	Hypertension (High Blood Pressure) 09/2013 - 06/2011
3	Exanthema (Rash) 03/2024 - 11/2009
3	Hemorrhage 01/2021 - 03/2010
3	Thrombocytopenia (Thrombopenia) 01/2021 - 08/2014
3	Renal Cell Carcinoma (Grawitz Tumor) 01/2016 - 01/2014
2	Multiple Myeloma 03/2024 - 01/2022
2	Muscular Atrophy (Muscle Atrophy) 01/2024 - 10/2022
2	Ovarian Epithelial Carcinoma 05/2022 - 02/2016
2	COVID-19 10/2021 - 01/2021
2	Adenocarcinoma 01/2019 - 09/2013
2	Body Weight (Weight, Body) 10/2018 - 07/2004
2	Nausea 09/2017 - 12/2012
2	Sudden Infant Death (SID) 08/2017 - 03/2016
2	Febrile Neutropenia 05/2013 - 11/2011
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 05/2012 - 01/2007
2	Peritoneal Neoplasms 03/2010 - 02/2009
2	Squamous Cell Carcinoma of Head and Neck 07/2006 - 01/2003
1	Atrophy 10/2022

Drug/Important Bio-Agent (IBA)

35	Trastuzumab (Herceptin)FDA Link 10/2023 - 02/2010
18	ErbB Receptors (EGF Receptor)IBA 08/2022 - 03/2005
17	Hormones (Hormone)IBA 03/2024 - 11/2009
14	human ERBB2 proteinIBA 03/2024 - 11/2009
13	Bevacizumab (Avastin)FDA Link 10/2014 - 01/2007
11	taxaneIBA 12/2020 - 04/2007
10	Docetaxel (Taxotere)FDA Link 01/2022 - 02/2010
9	Cisplatin (Platino)FDA LinkGeneric 12/2014 - 09/2003
7	Taxoids (Taxanes)IBA 03/2024 - 02/2008
7	Fulvestrant (Faslodex)FDA Link 11/2021 - 09/2017
7	Capecitabine (Xeloda)FDA Link 01/2021 - 08/2007
6	Paclitaxel (Taxol)FDA LinkGeneric 01/2024 - 12/2002
6	Biosimilar PharmaceuticalsIBA 01/2023 - 01/2018
6	Estrogen ReceptorsIBA 08/2017 - 06/2011
5	ixabepilone (BMS 247550)FDA Link 06/2013 - 08/2007
4	Epidermal Growth Factor (EGF)IBA 01/2020 - 11/2009
4	Gemcitabine FDA Link 09/2019 - 09/2003
4	AnthracyclinesIBA 10/2018 - 08/2007
4	pertuzumabIBA 01/2018 - 05/2012
4	Lapatinib (GW572016)FDA Link 05/2015 - 11/2009
3	Proteins (Proteins, Gene)FDA Link 03/2024 - 03/2005
3	Epirubicin (Ellence)FDA LinkGeneric 01/2024 - 12/2002
3	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2024 - 08/2016
3	Epinephrine (Adrenaline)FDA LinkGeneric 05/2022 - 03/2010
3	abemaciclibIBA 11/2021 - 09/2017
3	Fluorouracil (Carac)FDA LinkGeneric 01/2021 - 06/2006
3	ribociclibIBA 12/2020 - 01/2018
3	Ado-Trastuzumab EmtansineIBA 04/2020 - 10/2014
3	Carboplatin (JM8)FDA LinkGeneric 09/2019 - 02/2009
3	eribulin FDA Link 10/2018 - 09/2015
3	Tyrosine Kinase InhibitorsIBA 01/2017 - 11/2009
3	Sunitinib (Sutent)FDA Link 03/2014 - 05/2010
3	Aromatase InhibitorsIBA 03/2014 - 11/2009
2	Peptides (Polypeptides)IBA 03/2024 - 05/2012
2	AntigensIBA 03/2024 - 03/2010
2	Monoclonal AntibodiesIBA 03/2024 - 09/2011
2	trans-sodium crocetinate (crocetin)IBA 01/2023 - 10/2021
2	Oxygen (Dioxygen)IBA 01/2023 - 10/2021
2	GadoliniumIBA 01/2022 - 12/2020
2	Progesterone Receptors (Progesterone Receptor)IBA 08/2017 - 06/2013
2	Phenobarbital (Luminal)FDA Link 08/2017 - 01/2016
2	Analgesics (Analgesic Drugs)IBA 10/2016 - 10/2014
2	AndrogensIBA 08/2016 - 01/2013
2	PlatinumIBA 02/2016 - 03/2008
2	Everolimus FDA Link 01/2016 - 01/2014
2	Oxaliplatin (Eloxatin)FDA LinkGeneric 12/2014 - 02/2008
2	Letrozole (Femara)FDA LinkGeneric 06/2013 - 11/2009
2	thiamine triphosphorate (TTP)IBA 03/2013 - 06/2011
2	Cetuximab (Erbitux)FDA Link 03/2013 - 09/2011
2	cabazitaxel FDA Link 01/2013 - 07/2011
2	CreatinineIBA 12/2011 - 06/2011
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 06/2011 - 05/2008
2	Small Interfering RNA (siRNA)IBA 03/2011 - 12/2007
2	Irinotecan (Camptosar)FDA LinkGeneric 02/2008 - 09/2003
1	pyrotinibIBA 03/2024
1	Liposomes (Liposome)IBA 03/2024
1	Silicon Dioxide (Silica)FDA LinkGeneric 03/2024
1	bis(3- bis(4- chlorophenyl)methyl- 4- dimethylaminophenyl)amineIBA 01/2022
1	Radioisotopes (Radionuclides)IBA 01/2022

Therapy/Procedure

59	Drug Therapy (Chemotherapy) 01/2024 - 01/2003
41	Therapeutics 10/2022 - 06/2006
8	Adjuvant Chemotherapy 01/2023 - 10/2006
7	Neoadjuvant Therapy 03/2024 - 07/2006
7	Radiotherapy 01/2023 - 07/2011
4	Intravenous Infusions 01/2016 - 11/2010
3	Castration 01/2013 - 07/2011
2	Cytoreduction Surgical Procedures 05/2022 - 03/2010